Preliminary study of ovariectomy and chronic losartan-induced alterations in brain AT

Autor:	Danial, Mehranfard, Andrea, Linares, Alesa, Chabbra, Glenda, Campos, Aline M A, de Souza, Hong, Ji, Crystal, West, Kathryn, Sandberg, Robert C, Speth
Rok vydání:	2021
Předmět:	Male Ovariectomy Animals Brain Female Rats Long-Evans Angiotensin II Type 1 Receptor Blockers Drug Administration Schedule Losartan Receptor Angiotensin Type 1 Rats
Zdroj:	Brain research. 1766
ISSN:	1872-6240
Popis:	Women who undergo oophorectomy prior to the age of natural menopause have a higher risk of neurological and psychological impairment. Treatment with the angiotensin receptor blocker (ARB) losartan for 10 weeks following ovariectomy of Long-Evans rats at 3 months of age reduced the ovariectomy-induced cognitive decrements. Following completion of the behavioral experiments, (Campos et al., 2019), the brains were harvested for preliminary receptor autoradiographic studies of AT
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid________::344950ea35ae7f533f0b9399ad3e3f6f https://pubmed.ncbi.nlm.nih.gov/33991491 Zobrazit plný text záznamu Full Text from ScienceDirect