Recognition of viral and self-antigens by T

Autor:	Moira, Paroni, Virginia, Maltese, Marco, De Simone, Valeria, Ranzani, Paola, Larghi, Chiara, Fenoglio, Anna M, Pietroboni, Milena A, De Riz, Maria C, Crosti, Stefano, Maglie, Monica, Moro, Flavio, Caprioli, Riccardo, Rossi, Grazisa, Rossetti, Daniela, Galimberti, Massimiliano, Pagani, Elio, Scarpini, Sergio, Abrignani, Jens, Geginat
Rok vydání:	2016
Předmět:	Adult Male Multiple Sclerosis Fingolimod Hydrochloride Natalizumab Gene Expression Middle Aged Th1 Cells Autoantigens JC Virus Cytokines Humans Th17 Cells Female Antigens Viral Immunosuppressive Agents
Zdroj:	The Journal of allergy and clinical immunology. 140(3)
ISSN:	1097-6825
Popis:	Multiple sclerosis (MS) is an inflammatory demyelinating disease of the central nervous system (CNS) that is caused by autoreactive T cells and associated with viral infections. However, the phenotype of pathogenic T cells in peripheral blood remains to be defined, and how viruses promote MS is debated.We aimed to identify and characterize potentially pathogenic autoreactive T cells, as well as protective antiviral T cells, in patients with MS.We analyzed CD4TWe propose that autoreactive T
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid________::335051e68dd9823251c08ffb9db3cd0b https://pubmed.ncbi.nlm.nih.gov/28237728 Zobrazit plný text záznamu Full Text from ScienceDirect