Vitamin D esters are the major form of vitamin D produced by UV irradiation in mice

Autor:	Elizabeth G, Duchow, Izabela K, Sibilska-Kaminski, Lori A, Plum, Hector F, DeLuca
Rok vydání:	2021
Předmět:	Mice Ultraviolet Rays Animals Humans Esters Vitamin D Cholecalciferol Rats Skin
Zdroj:	Photochemicalphotobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology. 21(8)
ISSN:	1474-9092
Popis:	The primary source of vitamin D3 for humans is that produced in skin by ultraviolet irradiation. Ultraviolet (UV) B (UVB, 280-310 nm) light causes the isomerization of 7-dehydrocholesterol (7-DHC) to pre-vitamin D3 that is thermally isomerized to vitamin D3. In addition to free vitamin D3, it has been previously reported that esterified vitamin D3 is also found in the skin of rats irradiated with UVB. We found that a large fraction of the vitamin D3 precursor, 7-dehydrocholesterol is in the esterified form. Following UVB irradiation, vitamin D3 esters represent the majority of tissue vitamin D3, comprising approximately 80% in mice. Examination of vitamin D3 ester transport from skin in DBP
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid________::3342d2d43443d47a9c5dd4297ce9ac21 https://pubmed.ncbi.nlm.nih.gov/35488978 Zobrazit plný text záznamu Full text from SpringerLink