| Autor: |
L F, Panchenko, N N, Terebilina, V V, Malinovskaia, L S, Manakhova, O B, Petrichenko, A M, Balashov |
| Rok vydání: |
1990 |
| Předmět: |
|
| Zdroj: |
Voprosy meditsinskoi khimii. 36(3) |
| ISSN: |
0042-8809 |
| Popis: |
Content of Met-enkephalin in striatum and of beta-endorphin in rat hypophysis were estimated after administration of ethanol and alpha-interferon into the animals. Ethanol decreased Met-enkephalin content in striatum and of beta-endorphin in hypophysis. Preadministration of alpha-interferon into brain ventricles before ethanol administration led to an increase in concentration of Met-enkephalin, while content of beta-endorphin was unaltered. In peripheric administration alpha-interferon normalized content of beta-endorphin in adenohypophysis but did not affect the Met-enkephalin concentration. Effects of alpha-interferon on content of Met-enkephalin and beta-endorphin, related to dissimilar organization of the opiate systems in hypophysis and striatum tissues, are discussed. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
|
