Ion Channels, Transporters, and Sensors Interact with the Acidic Tumor Microenvironment to Modify Cancer Progression

Autor:	Ebbe, Boedtkjer
Rok vydání:	2021
Předmět:	Carcinogenesis Tumor Microenvironment Humans Breast Neoplasms Female Hydrogen-Ion Concentration Ion Channels
Zdroj:	Reviews of physiology, biochemistry and pharmacology. 182
ISSN:	0303-4240
Popis:	Solid tumors, including breast carcinomas, are heterogeneous but typically characterized by elevated cellular turnover and metabolism, diffusion limitations based on the complex tumor architecture, and abnormal intra- and extracellular ion compositions particularly as regards acid-base equivalents. Carcinogenesis-related alterations in expression and function of ion channels and transporters, cellular energy levels, and organellar H
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid________::331140592f056fb9eade1de0e2d62b7e https://pubmed.ncbi.nlm.nih.gov/34291319 Zobrazit plný text záznamu