Mucin-like carcinoma-associated antigen (mca) serum levels in breast-cancer - a critical-appraisal

Autor: A, Donadeo, V, Lorusso, G, Micelli, M, Quaranta, A, Muncipinto, F, Schittulli
Rok vydání: 2011
Zdroj: International journal of oncology. 2(2)
ISSN: 1019-6439
Popis: MCA serum levels were determined in 196 patients with benign breast disease (BD) and in 371 patients with breast cancer. MCA values were abnormal in 30.6% of the patients with BD. In breast cancer patients, significant increases were only found in metastatic disease (89.1%). MCA levels were not correlated with tumor size; on the contrary, the tumor marker showed a strict relation to axillary lymph node involvement. Moreover, the location of metastases and the number of sites involved seem to increase MCA concentrations. The MCA antigen seems to be a promising tool only for monitoring patients with advanced breast cancer.
Databáze: OpenAIRE