| Autor: |
Rashidat Oluwafunke, Ayanniyi, Fatimoh Idowu, Ojuade, Hidayah, Olumoh-Abdul, Kayode Muritala, Salawu, Haishat, Olufadi-Ahmed, Gbemisola Olusayo, Adebisi-Jose |
| Rok vydání: |
2019 |
| Předmět: |
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| Zdroj: |
Pakistan journal of pharmaceutical sciences. 32(1(Supplementary)) |
| ISSN: |
1011-601X |
| Popis: |
The leaf extract of Turraea vogelii Hook. f. ex. Benth. is used in ethnomedicine for the management of pain and inflammation. Anti-nociceptive activity was determined using acetic acid-induced mouse writhing model. The anti-inflammatory activity was investigated using in-vitro bovine serum albumin (BSA) denaturation assay and BSA-induced hind paw edema in rats. The extract (125-500 mg/kg) administered via the oral route produced a significant (p0.005) inhibition of acetic acid-induced writhes. The percent inhibition of writhes for extract (500 mg/kg) and diclofenac (10 mg/kg) was 53.3 and 59.5% respectively. The methanol extract (10 |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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