| Autor: |
J F, Quaranta, J P, Cassuto, R, Giacobi, R, Masseyeff |
| Rok vydání: |
1980 |
| Předmět: |
|
| Zdroj: |
Pathologie-biologie. 28(10) |
| ISSN: |
0369-8114 |
| Popis: |
Many authors have shown a progressive incidence of auto-antibodies in the elderly as age increases. Among the auto-antibodies found, the highest incidence concerns the Rheumatoid Factor (RF). Using an original enzyme-immunoassay of RF (RF-EIA), we were surprised to find a low incidence of RF in a sample of 100 healthy persons aged from 65 to 98 years (8%). Moreover, the finding of other auto-antibodies confirms this frequency inferior to other workers results. On the other hand, the level of present auto-antibodies is generally low, far below those usually found in auto-immune diseases. These results confirm a disturbance of the immune system in the elderly, but the levels observed make this disturbance more an humoral stigma of aging than a proof of a subjacent dysimmune disease. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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