Pt(IV)-Deferasirox Prodrug Combats DNA Damage Repair by Regulating RNA N

Autor:	Zheng-Yin, Pan, Yu-Yi, Ling, Hang, Zhang, Liang, Hao, Cai-Ping, Tan, Zong-Wan, Mao
Rok vydání:	2022
Předmět:	Deferasirox Iron Humans RNA Prodrugs Cisplatin Iron Chelating Agents Methylation DNA Damage
Zdroj:	Journal of medicinal chemistry. 65(21)
ISSN:	1520-4804
Popis:	DNA damage repair is considered to be an important mechanism of cisplatin resistance, and the roles of iron homeostasis in action mechanisms of cisplatin have not been studied yet. Herein, a Pt(IV) prodrug (
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid________::32476b5f49ea4b6949a0fae027819e5e https://pubmed.ncbi.nlm.nih.gov/36353870 Zobrazit plný text záznamu