Autor: |
J S, Dileep Kumar, Jaya, Prabhakaran, Naresh, Damuka, Justin Wayne, Hines, Skylar, Norman, Meghana, Dodda, J, John Mann, Akiva, Mintz, Kiran Kumar Solingapuram, Sai |
Rok vydání: |
2019 |
Předmět: |
|
Zdroj: |
Bioorganicmedicinal chemistry letters. 30(2) |
ISSN: |
1464-3405 |
Popis: |
Altered dynamics of microtubules (MT) are implicated in the pathophysiology of a number of brain diseases. Therefore, radiolabeled MT targeted ligands that can penetrate the blood brain barrier (BBB) may offer a direct and sensitive approach for diagnosis, and assessing the clinical potential of MT targeted therapeutics using PET imaging. We recently reported two BBB penetrating radioligands, [ |
Databáze: |
OpenAIRE |
Externí odkaz: |
|