Impact of inflammation on nutrition, iron status, and erythropoietin responsiveness in ESRD patients

Autor: B R, Bistrian, L A, Carey
Rok vydání: 2006
Předmět:
Zdroj: Nephrology nursing journal : journal of the American Nephrology Nurses' Association. 27(6)
ISSN: 1526-744X
Popis: Since many end stage renal disease (ESRD) patients experi inflammation, malnutrition, and anemia, the interplay of these processes should be considered in the approach to patients treated with erythropoietin (EPO). This article reviews the interrelationship between these factors. The systemic inflammatory response caused by exposure to inflammatory stimuli results in anorexia and metabolic disturbances leading to protein calorie malnut tion as well as sequestration of iron and hyporesponsiveness to EPO. The implications of these effects and possible strategies to optimize anemia management in the presence of these conditions are discussed.
Databáze: OpenAIRE