| Autor: |
T, Neway, H J, Boulouis, D, Thibault, C, Pilet |
| Jazyk: |
francouzština |
| Rok vydání: |
1992 |
| Předmět: |
|
| Zdroj: |
Comptes rendus de l'Academie des sciences. Serie III, Sciences de la vie. 315(1) |
| ISSN: |
0764-4469 |
| Popis: |
Intraperitoneal administration of polar glycopeptidolipids extracted from Mycobacterium chelonae (GPLp-Mc) has led to reversal of Doxorubicin-induced leucopenia in a manner comparable to that effected by GM-CSF administered in a dose of 100 IU (2.5 micrograms/kg). The mode of action and the toxicity of this product are being studied. Results obtained on the mouse indicate that it would be worthwhile to undertake tests in man aimed at studying the effect of GPLp-Mc on chemotherapy- and radiotherapy-induced leukopenias, once toxicological studies have been carried out. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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