Hb Las Palmas or alpha 2 beta 2(49)(CD8)Ser----Phe, a mildly unstable hemoglobin variant

Autor: J J, Malcorra-Azpiazu, M I, Balda-Aguirre, J C, Diaz-Chico, H, Hu, J B, Wilson, B B, Webber, F, Kutlar, A, Kutlar, T H, Huisman
Rok vydání: 1988
Předmět:
Zdroj: Hemoglobin. 12(2)
ISSN: 0363-0269
Popis: A new hemoglobin variant with a Ser----Phe substitution at position beta 49(CD8) was discovered in two members of a family living in the Canary Islands, Spain. Detection was by polyacrylamide gel electrophoresis and by reversed phase high performance liquid chromatography. The variant, which constituted 43% and 45%, respectively, in the two heterozygotes, was slightly unstable. Its presence did not affect hematological values though there was a mild reticulocytosis.
Databáze: OpenAIRE
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