Mucosal-Associated Invariant T Cells in Tumors of Epithelial Origin

Autor: Nicholas A, Zumwalde, Jenny E, Gumperz
Rok vydání: 2020
Předmět:
Zdroj: Advances in experimental medicine and biology. 1224
ISSN: 0065-2598
Popis: Mucosal-associated invariant T (MAIT) cells are innate T lymphocytes that circulate in blood and also reside in mucosal tissues. Blood MAIT cells are typically highly Th1-polarized, while those in mucosal tissues include both Th1- and Th17-polarized subsets. MAIT cells mount cytokine and cytolytic responses as a result of T cell receptor (TCR)-mediated recognition of microbially derived metabolites of riboflavin (vitamin B
Databáze: OpenAIRE