[Carcinogenic properties of diaphene NN]

Autor: L N, Pylev, T F, Kulagina, E E, Smetanin
Rok vydání: 1977
Předmět:
Zdroj: Voprosy onkologii. 23(12)
ISSN: 0507-3758
Popis: Carcinogenic activity of diaphene NN was studied in female mice of line CC57W. Weekly subcutaneous injections of 40 mg of diaphene induced tumors in 65% of mice (leucoses and local sarcomas). Instillations of 40 mg of diaphene per os (3-5 times per week) induced tumors in 39% of mice. In control mice tumors were found in 38% of cases, including 36% of leucoses. It is concluded that diaphene NN shows an insignificant carcinogenic activity.
Databáze: OpenAIRE