[Comparative evaluation of the protective effect of sodium valproate, phenazepam and ionol in stress-induced liver damage in rats]

Autor:	A A, Nikonorov, V P, Tverdokhlib
Rok vydání:	1991
Předmět:	Male Benzodiazepinones Valproic Acid Butylated Hydroxytoluene Antioxidants Rats Enzyme Activation Benzodiazepines Anti-Anxiety Agents Cytochrome P-450 Enzyme System Fructose-Bisphosphate Aldolase Microsomes Liver Animals Lipid Peroxidation Stress Psychological
Zdroj:	Fiziologicheskii zhurnal. 37(3)
ISSN:	0201-8489
Popis:	Ionol, a synthetic antioxidant, limits the stressor liver injury to a greater extent than sodium, valproate and phenazepam, activators of a GABA-ergic link of the stress-limiting organism systems. This injury is exhibited in the organospecific elevated levels of blood enzymes fructosediphosphate aldolase depression of N-demethylase activity of microsomal monooxygenases and a decrease in the amount of cytochromes P-450 and B5.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid________::31049199b9c34eae2d6a4719015ce322 https://pubmed.ncbi.nlm.nih.gov/1894054 Zobrazit plný text záznamu