[Changes in sensitivity of lymphocytic leukemia P388 cells to oxidative stress and platidiam upon tumor growth]

Autor: V V, Shaposhnikova, O E, Orlova, A A, Kudriavtsev, Iu N, Korystov
Rok vydání: 2003
Předmět:
Zdroj: Izvestiia Akademii nauk. Seriia biologicheskaia. (6)
ISSN: 1026-3470
Popis: We studied the effect of oxidative stress induced by hyperoxia, hydrogen peroxide, or menadione on mouse leukemia P388 cells at early (4 days) and late (7 days) stages of tumor growth. Oxidative stress proved to inhibit cell division and to induce apoptosis. Seven-day leukemia cells feature lower proliferative potential and higher sensitivity to oxidative stress and platidiam.
Databáze: OpenAIRE