[Benzylpenicillin efficacy for neutropenic infection prophylaxis in patients with cancer and postcytostatic neutropenia]

Autor: S V, Minenko, N V, Dmitrieva, K L, Chimishkian, N V, Zhukov, E N, Sokolova, V B, Larionova, V V, Ptushkin
Rok vydání: 2003
Předmět:
Zdroj: Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic]. 47(7)
ISSN: 0235-2990
Popis: Evaluation of benzylpenicillin (penicillin G) effect for infection prophylaxis at the oncological patients with severe postcytostatic neutropenia was performed. All the patients with neutrophils levels lower than 0.5 x 10(9)/L were recommended to use antibiotics for infection prophylaxis. Test-group (n = 40) used ciprofloxacin (0.5 g twice daily, per os) combined with benzylpenicillin (1.0 g four times daily, i/v); control group was treated by ciprofloxacin in the same dose only. Combination with benzylpenicillin resulted in statistically significant reduction of infections frequency among oncological patients.
Databáze: OpenAIRE