[Genetical aspects of surgical treatment in patients with hereditary breast cancer]
| Autor: | E M, Bit-Sava |
|---|---|
| Rok vydání: | 2015 |
| Předmět: |
Health Services Needs and Demand
Mammaplasty Ovariectomy Genes BRCA2 Genes BRCA1 Middle Aged Risk Assessment Survival Analysis Russia Salpingectomy Preventive Health Services Quality of Life Hereditary Breast and Ovarian Cancer Syndrome Humans Female Genetic Predisposition to Disease Genetic Testing Neoplasm Metastasis Mastectomy Neoplasm Staging |
| Zdroj: | Vestnik khirurgii imeni I. I. Grekova. 173(5) |
| ISSN: | 0042-4625 |
| Popis: | Numerous available results of investigations confirmed the important role of prophylactic bilateral laparoscopic salpingo-oophorectomy and contralateral prophylactic subcutaneous mastectomy in decrease of risks of malignant tumors of the reproductive system when mutation carriers of BRCA1 and BRCA2 presented. Recommendations to surgical treatment of hereditary breast cancer are considered as a very difficult task which should be based on risks and advantages of prophylactic surgical interventions. Presented surgical operations could be applied in mutation carriers of reparation DNA genes and patients with hereditary breast cancer aimed to improve the indices of general survival rate and quality of life. |
| Databáze: | OpenAIRE |
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