| Autor: |
V S, Hinshaw, F L, Schaffer, M A, Chatigny |
| Rok vydání: |
1976 |
| Předmět: |
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| Zdroj: |
Journal of the National Cancer Institute. 57(4) |
| ISSN: |
0027-8874 |
| Popis: |
Aerosols of the Moloney murine sarcoma virus (MuSV-M) and leukemia virus (MuLV-M) complex (MuSV-M/MuLV-M) were generated from refluxing atomizers and then aged in rotating drums at 21 degrees C holding temperature with relative humidities ranging from 25 to 76%. The MuSV-M and MuLV-M aerosolized from the same tumor extract preparation survived almost equally at the four humidity levels. Both viruses remained viable in the airborne state for at least 2 hours after aerosolization. When mice were exposed to airborne MuSV-M/MuLV-M, no macroscopic lesions were observed in lungs or other tissues examined during the 2-month postexposure period. On the basis of this study, MuSV-M was determined unsuitable as a "model system" in which a simple aerosol dose response could be used for biohazard evaluation of oncogenic virus aerosols. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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