Fibrinolytic agents: a new approach to the treatment of adult respiratory distress syndrome

Autor: R M, Hardaway, H, Harke, C H, Williams
Rok vydání: 1994
Předmět:
Zdroj: Advances in therapy. 11(2)
ISSN: 0741-238X
Popis: Nineteen patients suffering from adult respiratory distress syndrome (ARDS) secondary to trauma or sepsis, or both, failed to respond to treatment with mechanical ventilation with oxygen and positive end-expiratory pressure. On the premise that ARDS may be caused by the microclots of disseminated intravascular coagulation obstructing the pulmonary microcirculation, the patients were treated with either streptokinase or urokinase. Eighteen patients responded with significant improvement in PaO 2 value. No bleeding occurred and clotting parameters remained normal.
Databáze: OpenAIRE