DCE-MRI of the prostate using shutter-speed vs. Tofts model for tumor characterization and assessment of aggressiveness

Autor:	Stefanie J, Hectors, Cecilia, Besa, Mathilde, Wagner, Guido H, Jajamovich, George K, Haines, Sara, Lewis, Ashutosh, Tewari, Ardeshir, Rastinehad, Wei, Huang, Bachir, Taouli
Rok vydání:	2016
Předmět:	Male Image Processing Computer-Assisted Prostate Contrast Media Humans Prostatic Neoplasms Reproducibility of Results Neoplasm Invasiveness Middle Aged Image Enhancement Magnetic Resonance Imaging Retrospective Studies
Zdroj:	Journal of magnetic resonance imaging : JMRI. 46(3)
ISSN:	1522-2586
Popis:	To quantify Tofts model (TM) and shutter-speed model (SSM) perfusion parameters in prostate cancer (PCa) and noncancerous peripheral zone (PZ) and to compare the diagnostic performance of dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) to Prostate Imaging and Reporting and Data System (PI-RADS) classification for the assessment of PCa aggressiveness.Fifty PCa patients (mean age 60 years old) who underwent MRI at 3.0T followed by prostatectomy were included in this Institutional Review Board-approved retrospective study. DCE-MRI parameters (KDCE-MRI parameters were significantly different between TM and SSM and between PZ and PCa (P0.037). Diagnostic performances of TM and SSM for differentiation of PCa from PZ were similar (highest AUC TM: KSSM DCE-MRI did not increase the diagnostic performance of DCE-MRI for PCa characterization. PI-RADS outperformed both TM and SSM DCE-MRI for identification of aggressive cancer.3 Technical Efficacy: Stage 2 J. MAGN. RESON. IMAGING 2017;46:837-849.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid________::2fc9f163775ce769bc864fd701683474 https://pubmed.ncbi.nlm.nih.gov/28092414 Zobrazit plný text záznamu Plný text