| Autor: |
K, Lalwani, E B, Fox, R, Fu, B, Edmunds, L D, Kelly |
| Rok vydání: |
2012 |
| Předmět: |
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| Zdroj: |
Anaesthesia. 67(3) |
| ISSN: |
1365-2044 |
| Popis: |
Many anaesthetic agents affect intra-ocular pressure, yet little is known about nitrous oxide and intra-ocular pressure. This study assessed the effect of nitrous oxide on intra-ocular pressure in 20 healthy adult volunteers. The intra-ocular pressure was measured at baseline, while breathing a 70:30 mix of nitrous oxide and oxygen for 12 min, and then while breathing room air for 15 min. A linear mixed effects model was used to assess change in intra-ocular pressure over time. There was no significant difference in intra-ocular pressure between baseline and during or after nitrous oxide inhalation. Several differences in intra-ocular pressure were noted between internal time-points: pressure increased by 2.4 mmHg between 3 and 6 min of breathing nitrous oxide (p=0.01); it increased by 1.4 mmHg between 3 and 9 min of breathing nitrous oxide (p=0.046); and it decreased by 2.2 mmHg between 6 min of breathing nitrous oxide and 15 min of breathing room air (p=0.035). This study indicates that nitrous oxide inhalation does not significantly change intra-ocular pressure from baseline values in a population of healthy adults. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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