Logic-gated antibody pairs that selectively act on cells co-expressing two antigens

Autor:	Simone C, Oostindie, Derek A, Rinaldi, Gijs G, Zom, Michael J, Wester, Desiree, Paulet, Kusai, Al-Tamimi, Els, van der Meijden, Jennifer R, Scheick, Tessa, Wilpshaar, Bart, de Jong, Marloes, Hoff-van den Broek, Rachel M, Grattan, Janita J, Oosterhoff, Julie, Vignau, Sandra, Verploegen, Peter, Boross, Frank J, Beurskens, Diane S, Lidke, Janine, Schuurman, Rob N, de Jong
Rok vydání:	2021
Předmět:	Logic Complement C1q Antigens Surface Antibodies Monoclonal Antigens
Zdroj:	Nature biotechnology. 40(10)
ISSN:	1546-1696
Popis:	The use of therapeutic monoclonal antibodies is constrained because single antigen targets often do not provide sufficient selectivity to distinguish diseased from healthy tissues. We present HexElect
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid________::2f9d47a2d156096e415c018ab095c482 https://pubmed.ncbi.nlm.nih.gov/35879363 Zobrazit plný text záznamu Full text from SpringerLink