Non-extracorporeal circulation for coronary artery bypass graft surgery is more beneficial than extracorporeal circulation

Autor: F-Y, Yang, Y-Z, Bao, F-S, Liu, Y-C, Zhu, J, Zheng, J-H, Zhang, X-F, Zheng, G-C, Wei
Rok vydání: 2015
Předmět:
Zdroj: European review for medical and pharmacological sciences. 19(8)
ISSN: 2284-0729
Popis: The objective of this study was to compare coronary artery bypass graft (CABG) surgery with non-extracorporeal vs. extracorporeal circulation. The study outcomes included operative time, number of graft vessels, pulmonary infection rates, and systemic inflammatory markers.96 patients received selective CABG, either with non-extracorporeal (study group; n = 48) or extracorporeal circulation (control group; n = 48). Operative time, pulmonary infection rates, and blood levels of inflammatory markers TNF-α, IL-6, and IL-8 before and 4, 24, and 48 hours after the surgery were quantified. Graft vessels were quantified using computed tomography.Operative time was significantly shorter in study group (4.58 ± 0.91 vs. 5.36 ± 1.12 hours in control group; p0.05). The number of graft vessels and pulmonary infection rates were comparable between both techniques. However, systemic inflammatory markers were significantly (p0.05) lower in study group at 4 and, partly, 24 hours after the surgery.Extracorporeal circulation prolongs operation and can aggravate systemic inflammatory response. Therefore, CABG with non-extracorporeal circulation offers more beneficial outcomes.
Databáze: OpenAIRE