Dynamics of NADPH diaphorase activity in raphe neurons during chronic treatment with opiates

Autor: I V, Dyuizen, P A, Motavkin, V V, Shorin
Rok vydání: 2001
Předmět:
Zdroj: Bulletin of experimental biology and medicine. 132(3)
ISSN: 0007-4888
Popis: Systemic administration of diacetylmorphine considerably reduced the number of NADPH diaphorase-positive (NO-synthesizing) neurons in rat brain raphe nuclei. This effect was blocked by naloxone. In animals with the withdrawal syndrome NO-ergic activity in raphe neurons increased and surpassed the normal.
Databáze: OpenAIRE