Dynamics of NADPH diaphorase activity in raphe neurons during chronic treatment with opiates
Autor: | I V, Dyuizen, P A, Motavkin, V V, Shorin |
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Rok vydání: | 2001 |
Předmět: | |
Zdroj: | Bulletin of experimental biology and medicine. 132(3) |
ISSN: | 0007-4888 |
Popis: | Systemic administration of diacetylmorphine considerably reduced the number of NADPH diaphorase-positive (NO-synthesizing) neurons in rat brain raphe nuclei. This effect was blocked by naloxone. In animals with the withdrawal syndrome NO-ergic activity in raphe neurons increased and surpassed the normal. |
Databáze: | OpenAIRE |
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