| Autor: |
F, Kawasaki, P, Murat, Z, Li, T, Santner, S, Balasubramanian |
| Rok vydání: |
2017 |
| Předmět: |
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| Zdroj: |
Chemical communications (Cambridge, England). 53(8) |
| ISSN: |
1364-548X |
| Popis: |
We report the synthesis of a 5-formyl-2′-deoxyuridine (5fU) phosphoramidite and the preparation of oligonucleotides comprising all known, naturally observed eukaryotic thymidine modifications. Biophysical characterization of the synthetic oligonucleotides indicates that 5fU, but not the other T-derivatives, can alter DNA structures. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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