| Autor: |
Chih-Chun, Chang, Trinh Kieu, Dinh, Yi-An, Lee, Fu-Nien, Wang, Yun-Chieh, Sung, Pei-Lun, Yu, Shao-Chieh, Chiu, Yu-Chuan, Shih, Cheng-Yun, Wu, Yi-Da, Huang, Jane, Wang, Tsai-Te, Lu, Dehui, Wan, Yunching, Chen |
| Rok vydání: |
2020 |
| Předmět: |
|
| Zdroj: |
ACS applied materialsinterfaces. 12(40) |
| ISSN: |
1944-8252 |
| Popis: |
Antiangiogenic therapy is widely administered in many cancers, and the antiangiogenic drug sorafenib offers moderate benefits in advanced hepatocellular carcinoma (HCC). However, antiangiogenic therapy can also lead to hypoxia-driven angiogenesis and immunosuppression in the tumor microenvironment (TME) and metastasis. Here, we report the synthesis and evaluation of NanoMnSor, a tumor-targeted, nanoparticle drug carrier that efficiently codelivers oxygen-generating MnO |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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