| Autor: |
Raymond, Niaura, Bonnie, Spring, Belinda, Borrelli, Donald, Hedeker, Michael G, Goldstein, Nancy, Keuthen, Judy, DePue, Jean, Kristeller, Judy, Ockene, Allan, Prochazka, John A, Chiles, David B, Abrams |
| Rok vydání: |
2002 |
| Předmět: |
|
| Zdroj: |
Journal of consulting and clinical psychology. 70(4) |
| ISSN: |
0022-006X |
| Popis: |
The authors evaluated the efficacy of fluoxetine hydrochloride (Prozac; Eli Lilly and Company, Indianapolis, IN) as an adjunct to behavioral treatment for smoking cessation. Sixteen sites randomized 989 smokers to 3 dose conditions: 10 weeks of placebo, 30 mg, or 60 mg fluoxetine per day. Smokers received 9 sessions of individualized cognitive–behavioral therapy, and biologically verified 7-day self-reported abstinence follow-ups were conducted at 1, 3, and 6 months posttreatment. Analyses assuming missing data counted as smoking observed no treatment difference in outcomes. Pattern-mixture analysis that estimates treatment effects in the presence of missing data observed enhanced quit rates associated with both the 60-mg and 30-mg doses. Results support a modest, short-term effect of fluoxetine on smoking cessation and consideration of alternative models for handling missing data. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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