| Autor: |
Akram M, Amer, Azza M, Youssef, Hala S, El-Ozairy, Ahmed M, El-Hennawy |
| Rok vydání: |
2019 |
| Předmět: |
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| Zdroj: |
Brazilian journal of anesthesiology (Elsevier). 70(6) |
| ISSN: |
2352-2291 |
| Popis: |
Day-case pediatric sedation is challenging. Dexmedetomidine is a sedative analgesic that does not induce respiratory depression. We compared dexmedetomidine to propofol when it was added to ketamine for sedation during pediatric endoscopy, regarding recovery time and hemodynamic changes.We enrolled 120 patients (2-7 years in age) and randomly assigned them into two groups. Each patient received intravenous (IV) ketamine at a dose of 1 mg.kgThere was no significant difference in hemodynamics between the groups. The Propofol-Ketamine (P-K) group showed significantly shorter recovery times than the Dexmedetomidine-Ketamine (D-K) group (21.25 and 29.75 minutes respectively, p0.001). The P-K group showed more oxygen desaturation. Eleven and six patients experienced SpOThe P-K combination was associated with a shorter recovery time in pediatric upper gastrointestinal endoscopy, while the D-K combination showed less need for additional doses.Clinical trials.gov (NCT02863861). |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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