Sight-threatening varicella zoster virus infection after fludarabine treatment

Autor:	Y L, Chee, D J, Culligan, J A, Olson, P, Molyneaux, J B, Kurtz, H G, Watson
Rok vydání:	2000
Předmět:	Aged 80 and over Male Herpesvirus 3 Human Acyclovir Eye Infections Viral Retinal Necrosis Syndrome Acute Middle Aged Antiviral Agents Herpes Zoster Polymerase Chain Reaction DNA Viral Humans Female Waldenstrom Macroglobulinemia Lymphoma Follicular Immunosuppressive Agents Vidarabine Aged
Zdroj:	British journal of haematology. 110(4)
ISSN:	0007-1048
Popis:	Varicella zoster virus (VZV) infection involving the posterior segment of the eye after fludarabine treatment has not previously been described. Two patients, who had completed fludarabine treatment 3 and 18 months previously, presented with visual loss that had been preceded by a recent history of cutaneous zoster. The use of the polymerase chain reaction (PCR) for VZV DNA from ocular specimens allowed rapid confirmation of clinical diagnosis and treatment with a good outcome in one patient. With the increasing use of fludarabine and other purine analogues, an awareness of such complications is important because of their potentially sight-threatening consequences.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid________::2d895f0c39cfcccd98173e544a4dab79 https://pubmed.ncbi.nlm.nih.gov/11054072 Zobrazit plný text záznamu Plný text