| Autor: |
S A, Levakov, O V, Zaĭrat'iants, I S, Sidorova, K V, Opalenov, A G, Ali |
| Rok vydání: |
2007 |
| Předmět: |
|
| Zdroj: |
Arkhiv patologii. 69(2) |
| ISSN: |
0004-1955 |
| Popis: |
Various virus serotypes were found in 35.3% of cases and their detection rate frequency reducing with age. They were detectable in 35.3 -52.9% of cases of atypical glandular hyperplasia, highly and moderately differentiated adenocarcinoma of the endometrium and only in 17.6% of cases of poorly differentiated adenocarcinomas. Serotypes 58 and 51 were nearly twice more frequently, but serotypes 18 and 52 were not observed. Immunomorphologically virus-positive observations were characterized by pronounced infiltration with T-helper and T-suppressor/killer cells. The endometrium and tumors showed an increased significant proliferative activity (Ki-67 expression) and reduced expression of receptors to progesterone and, to a lesser degree, to estrogen in 47-83% of virus-positive cases. Expression of growth factors did not greatly differ. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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