Plasma creatine kinase isozyme electrophoretic pattern of long-term vitamin E-deficient rats

Autor:	L H, Chen, R R, Thacker
Rok vydání:	1983
Předmět:	Brain Chemistry Electrophoresis Isoenzymes Time Factors Muscles Animals Vitamin E Rats Inbred Strains Vitamin E Deficiency Creatine Kinase Rats
Zdroj:	International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition. 53(2)
ISSN:	0300-9831
Popis:	Weanling male Sprague Dawley rats were fed a vitamin E-deficient basal diet with or without supplementation of 100 IU/kg diet of vitamin E for 12 months. The isozyme pattern of creatine kinase (CPK) in plasma was determined electrophoretically. The CPK activity of the plasma of control rats averaged 43.2 nmoles/min/ml and was predominantly CPK3 isozyme, while that of the plasma of vitamin E-deficient rats averaged 100.8 nmoles/min/ml and consisted of CPK2 and CPK3 isozymes. The results suggest that the increased CPK activity in the plasma of vitamin E-deficient rats may originate from heart and skeletal muscle degeneration.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid________::2d1cb4d9f6e7c59f9bbbe695b0ca3a67 https://pubmed.ncbi.nlm.nih.gov/6885273 Zobrazit plný text záznamu