Serum CEA level lost its prognostic value in gastric cancer patients with AB blood type

Autor: Xiao, Shuao, Feng, Fan, Sun, Li, Cai, Lei, Yang, Xuewen, Wang, Wenbin, Zhou, Wei, Lian, Xiao, Zhang, Hongwei
Jazyk: angličtina
Rok vydání: 2017
Předmět:
Popis: Background: Little is known about the relationship between ABO blood groups and serum CEA level in gastric cancer patients. The aim of this study was to investigate the prognostic value of serum CEA level in gastric cancer patients with different ABO blood types. Materials and Methods: From September 2008 to April 2015, a total of 3234 gastric cancer patients who underwent radical gastrectomy were retrospectively analyzed in our institution. The clinicopathological characteristics and survivals were recorded. The prognostic value of serum CEA level within different ABO blood groups were analyzed. Results: The ratio of male to female patients was 3.5:1. The median age was 57.4 years (range 20-87). In all, 980 cases (30.3%) were blood type A, 935 cases (28.9%) were blood type B, 331 cases (10.2%) were blood type AB and 988 cases (30.6%) were blood type O. The positive rate of preoperative serum CEA was 19.0%. The overall survival of patients with negative and positive CEA level were 60.2% vs 34.4% for A blood type (P
Databáze: OpenAIRE