| Autor: |
D K, Luyt, J, Pridgeon, J, Brown, G, Peek, R, Firmin, H C, Pandya |
| Rok vydání: |
2005 |
| Předmět: |
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| Zdroj: |
Acta paediatrica (Oslo, Norway : 1992). 93(12) |
| ISSN: |
0803-5253 |
| Popis: |
To describe the short-term outcome of children with meningococcal sepsis treated with extracorporeal membrane oxygenation (ECMO) in a single centre.Retrospective analysis of case notes.The Heartlink ECMO Centre, Glenfield Hospital, Leicester.Eleven children (8 boys) out of a total caseload of 800 patients were treated for meningococcal sepsis with ECMO.Extracorporeal membrane oxygenation.All children with meningococcal sepsis treated with ECMO had a Glasgow Meningococcal Septicaemia Prognostic Score (GMSPS)or = 12 (positive predictive risk of death of approximately 90%). Five children had adult respiratory distress syndrome (ARDS) and six had refractory shock with multi-organ dysfunction syndrome (MODS) at presentation for ECMO. All five children in the ARDS group survived, four of five receiving veno-venous (VV-) ECMO therapy. In contrast, only one of six children with refractory shock with MODS survived, all of whom required veno-arterial (VA-) ECMO therapy.Most children with meningococcal sepsis and severe ARDS can be successfully treated with VV-ECMO. In contrast, children with refractory shock and MODS die despite treatment with VA-ECMO. This report does not resolve whether ECMO therapy offers any advantage over conventional therapy in treating severe meningococcal sepsis. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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