| Autor: |
Jian Qing, Wang, Zhi Juan, Li, Hui, Gao, Jie, Sheng, Chun Mei, Liang, Ya Bin, Hu, Xun, Xia, Kun, Huang, Su Fang, Wang, Peng, Zhu, Jia Hu, Hao, Fang Biao, Tao |
| Rok vydání: |
2021 |
| Předmět: |
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| Zdroj: |
Biomedical and environmental sciences : BES. 35(8) |
| ISSN: |
2214-0190 |
| Popis: |
Prenatal phthalate exposure has been associated with placental inflammatory factors and infant allergic rhinitis (AR). However, the results are inconclusive. We designed a population-based cohort study to examine the effects of placental inflammatory biomarkers on the sex-dependent associations between maternal phthalate exposure and infant AR.A total of 2,348 pregnant women from Ma'anshan, Anhui Province, China, who were screened before antenatal visits and met the inclusion criteria, were included in the present study. We assessed AR in their offspring aged 36 months with a questionnaire. Quantitative PCR was performed to measure placental inflammatory factor mRNAs. The independent samplesChildhood AR may be related to education and family monthly income (The associations of maternal MEHHP and MEOHP levels with fetal AR in males were significant. Placental HO-1 was a fractional mediator in the associations between MEHHP and AR. Thus, the placenta should be further investigated as a potential mediator of maternal exposure-induced disease risk in children. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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