Effect of calcium and vitamin D supplementation with and without collagen peptides on bone turnover in postmenopausal women with osteopenia
| Autor: | Chrysoula, Argyrou, Efthymia, Karlafti, Kalliopi, Lampropoulou-Adamidou, Symeon, Tournis, Konstantinos, Makris, George, Trovas, Ismene, Dontas, Ioannis K, Triantafyllopoulos |
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| Rok vydání: | 2020 |
| Předmět: |
Bone Turnover Markers
Osteopenia Calcium Supplement Calcium Compounds Middle Aged Peptide Fragments Postmenopausal Women Postmenopause Bone Diseases Metabolic Treatment Outcome Bone Density Dietary Supplements Lactates Humans Drug Therapy Combination Female Original Article Bone Remodeling Collagen Aged Cholecalciferol Collagen Peptides |
| Zdroj: | Journal of Musculoskeletal & Neuronal Interactions |
| ISSN: | 1108-7161 |
| Popis: | Objectives: Collagen peptides (CPs) seem to exert beneficial effects on bone and may have a role as a treatment option. In the present randomized prospective study, we aimed to examine the efficacy, as expressed by changes in P1NP and CTX, and the tolerability of 3-month supplementation of calcium, vitamin D with or without bioactive CPs in postmenopausal women with osteopenia. Methods: Fifty-one female, postmenopausal women with osteopenia were allocated to two groups: Group A received a sachet containing 5 g CPs, 3.6 g calcium lactate (equivalent to 500 mg of elemental calcium) and 400 IU vitamin D3 and group B received a chewable tablet containing 1.25 g calcium carbonate (equivalent to 500 mg of elemental calcium) and 400 IU vitamin D3 daily. Results: In group A, the P1NP levels significantly decreased by 13.1% (p |
| Databáze: | OpenAIRE |
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