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Autor: Chrishan S, Samuel, Yifang, Li, Yan, Wang, Robert E, Widdop
Rok vydání: 2022
Zdroj: British journal of pharmacology.
ISSN: 1476-5381
Popis: Class A rhodopsin-like G protein-coupled receptors (GPCRs) are by far the largest class of GPCRs, and are integral membrane proteins that are used by various cells to convert extracellular signals into intracellular responses. Initially, class A GPCRs were believed to function as monomers, but a growing body of evidence has emerged to suggest that these receptors can function as homo- and heterodimers, and undergo functional crosstalk to influence the actions of agonists or antagonists acting at each receptor. This review will focus on the angiotensin type 1 (AT
Databáze: OpenAIRE