Antisense Inhibition of Protein Tyrosine Phosphatase 1B With IONIS-PTP-1B
| Autor: | Andres, Digenio, Nguyen C, Pham, Lynnetta M, Watts, Erin S, Morgan, Shiangtung W, Jung, Brenda F, Baker, Richard S, Geary, Sanjay, Bhanot |
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| Rok vydání: | 2017 |
| Předmět: |
Adult
Blood Glucose Male Protein Tyrosine Phosphatase Non-Receptor Type 1 Body Weight Middle Aged Overweight Metformin Oligodeoxyribonucleotides Antisense Sulfonylurea Compounds Diabetes Mellitus Type 2 Double-Blind Method Oligodeoxyribonucleotides Weight Loss Humans Hypoglycemic Agents Drug Therapy Combination Female Obesity Insulin Resistance Aged |
| Zdroj: | Diabetes care. 41(4) |
| ISSN: | 1935-5548 |
| Popis: | To evaluate safety and efficacy of IONIS-PTP-1BIn this phase II, double-blind, randomized, placebo-controlled, multicenter trial, overweight and obese patients (BMI ≥27 kg/mMean baseline HbACompared with placebo, IONIS-PTP-1B |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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