| Autor: |
S, Lucangioli, G, Fernández Otero, V, Rodríguez, C N, Carducci |
| Rok vydání: |
1996 |
| Předmět: |
|
| Zdroj: |
Bollettino chimico farmaceutico. 135(6) |
| ISSN: |
0006-6648 |
| Popis: |
A liquid chromatographic method was developed for the simultaneous separation and determination of noscapine hydrochloride, hexylresorcinol and anethole in cough lozenges. Analysis was performed on a phenyl column with phosphate buffer- acetonitrile as mobile phase and the separated components were detected at 282 mm. Recoveries obtained for the analytes were of 94.6% for noscapine hydrochloride, 99.1% for hexylresorcinol and 96.3% for anethole. The values of the relative standard deviation were 0.8% for noscapine hydrochloride, 1.5% for hexylresorcinol and 1.1% for anethole. The analytical method was validated and a system suitability test was accomplished for the chromatographic method. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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