Outcomes of surgical treatment alone in patients with superficial soft tissue sarcoma regardless of size or grade

Autor:	Janice L, Austin, Walley J, Temple, Shannon, Puloski, Norman S, Schachar, Elizabeth, Oddone Paolucci, Elizabeth, Kurien, Kourosh, Sarkhosh, Lloyd A, Mack
Rok vydání:	2015
Předmět:	Adult Male Patient Selection Sarcoma Kaplan-Meier Estimate Middle Aged Disease-Free Survival Medical Records Alberta Treatment Outcome Humans Female Registries Neoplasm Grading Neoplasm Recurrence Local Aged Retrospective Studies
Zdroj:	Journal of surgical oncology. 113(1)
ISSN:	1096-9098
Popis:	Currently, standard treatment of soft tissue sarcoma (STS) is wide local excision and adjuvant radiation, but radiation may be unnecessary in superficial STS. The primary objective is to assess local recurrence rates in patients treated with surgical management alone for superficial STS.A retrospective cancer registry review of patients treated with surgery alone for superficial STS at the Tom Baker Cancer Center (TBCC) was performed. Patient and tumor characteristics as well as recurrence data were collected.Sixty-one patients met study criteria. Local and overall recurrence rates were 7/61 (11.5%) and 12/61 (19.7%), respectively. The proportion with a T2 tumor was 38.8% versus 33.3% (P = 0.69), with Grade 2 or 3 tumors was 59.2% versus 83.3% (P = 0.14), and with resection margins1 cm was 28.6% versus 75.0% (P = 0.008) for patients without and with recurrence, respectively. Median time to recurrence was 1.7 (0.4-5.2) years.Surgical resection alone appears to be a viable option for superficial STS that can save patients from potential side effects of radiation. The association between recurrence and inadequate margins (1 cm) requires additional treatment be offered to this subset of patients.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid________::29ee989c963cd70db9709e87c7e7d703 https://pubmed.ncbi.nlm.nih.gov/26661586 Zobrazit plný text záznamu Plný text