| Autor: |
Xiang-Dong, Lu, Liang-Liang, Cui, Yan, Ma, Rong-Qiang, Zu, Tao, Shen, Jiang-Qing, Li, Jian-Xiang, Yao, Jun, Shan, Qi, Xie, Chao, Shi, Guang, Zeng |
| Rok vydání: |
2013 |
| Předmět: |
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| Zdroj: |
Zhonghua liu xing bing xue za zhi = Zhonghua liuxingbingxue zazhi. 33(10) |
| ISSN: |
0254-6450 |
| Popis: |
To study the source of infection, the scope of epidemic and control measures in an outbreak involving students having symptoms as fever, dizziness, headache, vomiting and nausea.The suspected-case was defined as fever (armpit temperature ≥ 37°C) and with one or more of the following symptoms: dizziness, headache, vomiting and nausea, among students and teachers at school from Mar 1, 2012. Confirmed-case was among suspected case accompanied by both throat and rectal swabs enterovirus positive by RT-PCR. All the cases were collected through checking the medical records from 4 hospitals as well as through the absence records of students and teachers, from Mar 1, 2012. We conducted a case-control study with ratio of 1:2 and data on the exposures to water among students and teachers was collected prior to the illness. 27 cases' throat and rectal swabs were collected and analyzed by RT-PCR and PCR sequence methods. 2 warm-water samples were collected for testing the counts on total bacteria and E. coli.103 students' cases were identified in school L, with the attack rate as 4.6% (103/2255). Students from Grade three had the high attack rate as 18.1% (72/397) and 77.7% (80/103) of the cases located in the building with 'multiple-functions'. Epidemic curve of the outbreak showed a pattern with continuous common source of infection. It seemed that the exposure to warm-water appeared to be the major risk factor (OR = 18.3, 95%CI: 2.0 - 169.5) together with the intake of un-boiled water (OR = 15.5, 95%CI: 1.7 - 141.8). Specimens from 27 students (81.5%, 22/27) were identified enterovirus positive by RT-PCR, and 7 of the 9 students were confirmed carrying Echo 30. Bacteria and coli were negative from the 2 warm-water samples.This viral meningitis-outbreak was caused by Echo 30, with drinking water as the major risk factor. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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