Bacteriophage lambda PaPa: not the mother of all lambda phages

Autor: R W, Hendrix, R L, Duda
Rok vydání: 1992
Předmět:
Zdroj: Science (New York, N.Y.). 258(5085)
ISSN: 0036-8075
Popis: The common laboratory strain of bacteriophage lambda--lambda wild type or lambda PaPa--carries a frameshift mutation relative to Ur-lambda, the original isolate. The Ur-lambda virions have thin, jointed tail fibers that are absent from lambda wild type. Two novel proteins of Ur-lambda constitute the fibers: the product of stf, the gene that is disrupted in lambda wild type by the frameshift mutation, and the product of gene tfa, a protein that is implicated in facilitating tail fiber assembly. Relative to lambda wild type, Ur-lambda has expanded receptor specificity and adsorbs to Escherichia coli cells more rapidly.
Databáze: OpenAIRE