| Autor: |
Jiale, Tang, Zhonghua, Liao, Liying, Luo, Shuanglinzi, Deng, Yuanyuan, Jiang, Fangyuan, Wang, Xinyue, Hu, Hongling, Yin, Guanghui, Gong, Juntao, Feng, Xiaozhao, Li |
| Rok vydání: |
2022 |
| Předmět: |
|
| Zdroj: |
Frontiers in immunology. 13 |
| ISSN: |
1664-3224 |
| Popis: |
Monocytes are involved in the pathogenesis of ANCA-associated vasculitis (AAV). Monocyte/macrophages are the dominant infiltrating cells in the glomeruli of patients with myeloperoxidase-AAV (MPO-AAV). However, how human monocyte subsets extravasate to the kidney in MPO-AAV with renal damage is unclear.30 MPO-AAV patients with renal damage and 22 healthy controls were enrolled in this study. Monocyte subsets and monocyte-related chemokines in the blood and kidneys of MPO-AAV patients were detected. The chemoattractant activity of the CX3CL1-CX3CR1 axis on CD16Compared with controls, CD16Enhanced extravasation of CD16 |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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