HLA-DPB1 alleles in house dust mite allergic patients

Autor: R M, O'Brien, B D, Tait, M D, Varney, W R, Thomas
Rok vydání: 1999
Předmět:
Zdroj: European journal of immunogenetics : official journal of the British Society for Histocompatibility and Immunogenetics. 26(4)
ISSN: 0960-7420
Popis: Associations were sought between the presence of allergic sensitivity to Der p 1, a major allergen from the house dust mite, and the HLA-DPB1 genotype. Whilst allergic patients did not differ from controls in DPB1 allelic distribution, there was a correlation of DPB1*11011 with strongly reactive T-cell proliferative responses to Der p 1 and high titre specific IgE to Dermatophagoides pteronyssinus.
Databáze: OpenAIRE