| Autor: |
M, Lebel, J G, Lachance, J H, Grose |
| Rok vydání: |
1981 |
| Předmět: |
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| Zdroj: |
Biomedicine / [publiee pour l'A.A.I.C.I.G.]. 35(3) |
| ISSN: |
0300-0893 |
| Popis: |
Plasma renin activity (PRA) was measured after repetitive furosemide stimulations in 16 normotensive homotransplanted patients who previously had bilateral nephrectomies. The percentage PRA response to furosemide was very low (34%) in the immediate period after transplantation, but increased progressively with time to a level after one year (111%) which was not statistically different from age and sex matched control subjects. A significant correlation was found between the percentage PRA increase and the number of weeks after transplantation (r = 0.48, P less than 0.01). These data indicate that the juxtaglomerular cell responsiveness to furosemide is quantitatively time dependent after transplantation, and it is a factor that should be considered in the evaluation of renin-angiotensin system in such patients. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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