Iterative Arylation of Amino Acids and Aliphatic Amines via δ-C(sp

Autor: Srimanta, Guin, Pravas, Dolui, Xinglong, Zhang, Satyadip, Paul, Vikas Kumar, Singh, Sukumar, Pradhan, Hediyala B, Chandrashekar, S S, Anjana, Robert S, Paton, Debabrata, Maiti
Rok vydání: 2019
Zdroj: Angewandte Chemie (International ed. in English). 58(17)
ISSN: 1521-3773
Popis: Directed C-H functionalization has been realized as a complementary tool to the traditional approaches for a straightforward access of non-proteinogenic amino acids; albeit such a process is restricted mostly up to the γ-position. In the present work, we demonstrate the diverse (hetero)arylation of amino acids and analogous aliphatic amines selectively at the remote δ-position by tuning the reactivity controlled by ligands. An organopalladium δ-C(sp
Databáze: OpenAIRE