| Autor: |
E, Rondeau, J, Cerrina, F, Delarue, F L, Ladurie, P, Hervé, A, Chapelier, P, Dartevelle, J D, Sraer |
| Jazyk: |
francouzština |
| Rok vydání: |
1991 |
| Předmět: |
|
| Zdroj: |
Presse medicale (Paris, France : 1983). 20(40) |
| ISSN: |
0755-4982 |
| Popis: |
In 10 patients who received a heart lung transplant, TNF-alpha generation by cells collected during bronchioloalveolar lavages (n = 30) and by circulating mononuclear cells was measured. Basal and recombinant IL-2-stimulated productions (50 U/ml) were measured. TNF-alpha concentration was determined by an immunoradiometric assay (IRMA). Circulating mononuclear cells produced at least 4 times less TNF-alpha than BAL cells. Rejection episodes or CMV diseases were not associated with significant changes in TNF-alpha generation. Recombinant IL-2 increased this production in both cell populations but the magnitude of this effect was smaller in BAL cells, suggesting an in vivo preactivation. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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