| Autor: |
A A, Ostanin, E R, Chernykh, G Z, Shubinskiĭ, V I, Nekipelova, N L, Tov, V P, Lozovoĭ |
| Rok vydání: |
1991 |
| Předmět: |
|
| Zdroj: |
Vestnik Akademii meditsinskikh nauk SSSR. (12) |
| ISSN: |
0002-3027 |
| Popis: |
The common features of the pathogenesis of chronic lymphocytic leukemia (CLL) and chronic glomerulonephritis (CGN) have been shown as a result of a comprehensive study of the functional properties of B cells. Both CLL and CGN are accompanied by the appearance and accumulation of different types of activated B cells characterized by high spontaneous proliferation and/or Ig secretion; or sensitivity to T cell growth and differentiation factors; or capacity for Ig secretion; in mitomycin C treated B cell cultures (i.e. without previous proliferation). The present data may be useful in the integral evaluation of B cell function in health and in immunopathologies (lymphoproliferative and autoimmune/immune complex diseases). |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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