End-to-End Automated Synthesis of C(sp

Autor: Irini, Abdiaj, Santiago, Cañellas, Alejandro, Dieguez, Maria Lourdes, Linares, Brenda, Pijper, Alberto, Fontana, Raquel, Rodriguez, Andres, Trabanco, Eduardo, Palao, Jesus, Alcázar
Rok vydání: 2022
Zdroj: Journal of medicinal chemistry.
ISSN: 1520-4804
Popis: Herein, we report an end-to-end process including synthesis, work-up, purification, and post-purification with minimal human intervention using Negishi coupling as a key transformation to increase Fsp
Databáze: OpenAIRE